Before the Flintstones were selling vitamins, they were selling Winston cigarettes.  Here is a 1961 Flintstones Winston commercial.

[via dabble]

Previously:
Classic Jell-O commercial, Classic Butter Ball Turkey Commercial from 1959, Vintage Folgers Coffee Commercials, Classic Wilkins Coffee Jim Henson Ads, 1960s Commercial: Cock O' The Walk low calorie fruit cocktail