Rybelsus is a drug used to control glycemic levels in patients with type 2 diabetes mellitus. Its active ingredient is semaglutide, an analogue of GLP-1, a physiological hormone that regulates glucose concentration and appetite, as well as the cardiovascular system. Despite the many benefits of this medicine, which effectively helps control blood sugar levels, reduce body weight and reduce body fat, Rybelsus has a number of side effects. The most commonly reported adverse reactions are from the gastrointestinal tract, including nausea, diarrhea and vomiting. Like all drugs used to control type 2 diabetes, Rybelsus has undergone numerous clinical studies on its safety profile, which made it possible to clearly classify possible side effects by the organ systems in which they occur and the frequency of manifestations.
The side effects that appear more often than all others (according to WHO recommendations, they are designated as very often occurring) include: from the side of metabolism and nutrition – hypoglycemia when used together with insulin or sulfonylurea derivatives; from the gastrointestinal tract – nausea and diarrhea.
Frequently occurring side effects, which can also develop from metabolism and nutrition, are hypoglycemia when used together with other PHGPs, as well as decreased appetite. The organ of vision often develops such undesirable reactions as complications of diabetic retinopathy. These may include the need for retinal photocoagulation, the need for intravitreal drug administration, vitreous hemorrhage, and even the development of diabetes-related blindness. Common side effects that develop from the gastrointestinal tract include vomiting, abdominal pain, bloating, constipation, dyspepsia, gastritis, gastroesophageal reflux disease, flatulence. Fatigue is a common disorder. According to the results of laboratory and instrumental data, an increase in the activity of lipase and amylase is often observed.
Infrequent side effects of Rybelsus include: from the heart – increased heart rate, from the gastrointestinal tract – belching, from the liver and biliary tract – cholelithiasis, and among common conditions – weight loss. Rarely observed adverse reactions are anaphylactic reactions from the immune system, as well as acute pancreatitis from the gastrointestinal tract.
All these undesirable reactions have their own characteristics. For example, hypoglycemia is mainly observed when Rybelsus is used in combination with sulfonylureas or insulin. As for adverse reactions from the gastrointestinal tract, most of them are mild to moderate in severity and disappear some time after starting to take the drug. Most often, patients report any side effects in the first two to three months of therapy.
It should be noted that taking Rybelsus is only advisable long-term, so you should come to terms with the almost inevitable side effects in the first 2-3 months of therapy. Purchasing one dosage of medication for the entire treatment period is not a good idea, because at first the therapy is carried out in smaller dosages. However, you can immediately buy all three options, namely 3, 7 and 14 mg, to save money. It is optimal to buy Rybelsus online https://mdisite.com/rybelsus-coupon/, this way you will be able to save at least 15% of the cost of the medicine, and with a successful combination of circumstances, two to three times more thanks to discount programs and discount coupons.
